Abstract

Endothelium-derived relaxing factor is a potent endogenous vasodilator. This substance is now known to be nitric oxide, which is derived from the metabolism of L-arginine. This potent vasodilator also inhibits interactions of circulating blood elements with the vessel wall. Platelet adherence and aggregation, as well as monocyte adherence and infiltration, are regulated by this paracrine factor. By virtue of these characteristics, nitric oxide inhibits atherogenesis.

Original languageEnglish (US)
Pages (from-to)1-8
Number of pages8
JournalDisease Management and Health Outcomes
Volume2
Issue numberSUPPL. 1
DOIs
StatePublished - 1997

ASJC Scopus subject areas

  • Leadership and Management
  • Nursing(all)
  • Health Policy

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