Abstract
Endothelium-derived relaxing factor is a potent endogenous vasodilator. This substance is now known to be nitric oxide, which is derived from the metabolism of L-arginine. This potent vasodilator also inhibits interactions of circulating blood elements with the vessel wall. Platelet adherence and aggregation, as well as monocyte adherence and infiltration, are regulated by this paracrine factor. By virtue of these characteristics, nitric oxide inhibits atherogenesis.
Original language | English (US) |
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Pages (from-to) | 1-8 |
Number of pages | 8 |
Journal | Disease Management and Health Outcomes |
Volume | 2 |
Issue number | SUPPL. 1 |
DOIs | |
State | Published - 1997 |
ASJC Scopus subject areas
- General Nursing
- Leadership and Management
- Health Policy