Patent Ductus Arteriosus with Left to Right Shunting Exacerbating Aortic Valve Stenosis

Paulamy Ganguly; Zhihao Zhu; Suhas Babu; Nandan Shettigar; Valeria Duarte; C. Huie Lin

doi:10.14797/mdcvj.1514

Patent Ductus Arteriosus with Left to Right Shunting Exacerbating Aortic Valve Stenosis

Paulamy Ganguly, Zhihao Zhu, Suhas Babu, Nandan Shettigar, Valeria Duarte, C. Huie Lin

Research output: Contribution to journal › Article › peer-review

Abstract

Aortic stenosis (AS) leads to a reduced effective orifice of the aortic valve, and severity is based on obstructions in flow and velocity. In some patients, coexisting structural cardiac abnormalities that increase left ventricular volume, such as patent ductus arteriosus (PDA), may complicate evaluation and management. We present the case of a patient with severe AS and unrepaired PDA and discuss the hemodynamic implications and important physiological changes resulting from the interactions between these lesions. It is important for clinicians to consider the impact of PDA closure in the evolution of AS and related symptoms.

Original language	English (US)
Pages (from-to)	39-43
Number of pages	5
Journal	Methodist DeBakey cardiovascular journal
Volume	21
Issue number	1
DOIs	https://doi.org/10.14797/mdcvj.1514
State	Published - 2025

Keywords

aortic valve stenosis
congenital heart disease
interventional cardiology
patent ductus arteriosus
PDA closure
TAVR

ASJC Scopus subject areas

General Medicine

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10.14797/mdcvj.1514

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title = "Patent Ductus Arteriosus with Left to Right Shunting Exacerbating Aortic Valve Stenosis",

abstract = "Aortic stenosis (AS) leads to a reduced effective orifice of the aortic valve, and severity is based on obstructions in flow and velocity. In some patients, coexisting structural cardiac abnormalities that increase left ventricular volume, such as patent ductus arteriosus (PDA), may complicate evaluation and management. We present the case of a patient with severe AS and unrepaired PDA and discuss the hemodynamic implications and important physiological changes resulting from the interactions between these lesions. It is important for clinicians to consider the impact of PDA closure in the evolution of AS and related symptoms.",

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AU - Ganguly, Paulamy

AU - Zhu, Zhihao

AU - Babu, Suhas

AU - Shettigar, Nandan

AU - Duarte, Valeria

AU - Lin, C. Huie

PY - 2025

Y1 - 2025

N2 - Aortic stenosis (AS) leads to a reduced effective orifice of the aortic valve, and severity is based on obstructions in flow and velocity. In some patients, coexisting structural cardiac abnormalities that increase left ventricular volume, such as patent ductus arteriosus (PDA), may complicate evaluation and management. We present the case of a patient with severe AS and unrepaired PDA and discuss the hemodynamic implications and important physiological changes resulting from the interactions between these lesions. It is important for clinicians to consider the impact of PDA closure in the evolution of AS and related symptoms.

AB - Aortic stenosis (AS) leads to a reduced effective orifice of the aortic valve, and severity is based on obstructions in flow and velocity. In some patients, coexisting structural cardiac abnormalities that increase left ventricular volume, such as patent ductus arteriosus (PDA), may complicate evaluation and management. We present the case of a patient with severe AS and unrepaired PDA and discuss the hemodynamic implications and important physiological changes resulting from the interactions between these lesions. It is important for clinicians to consider the impact of PDA closure in the evolution of AS and related symptoms.

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KW - congenital heart disease

KW - interventional cardiology

KW - patent ductus arteriosus

KW - PDA closure

KW - TAVR

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Patent Ductus Arteriosus with Left to Right Shunting Exacerbating Aortic Valve Stenosis

Abstract

Keywords

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