Paraspinal muscle asymmetry in Parkinson's disease

William G. Ondo, Hani A. Haykal

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Lateral postural deviation in Parkinson's disease (PD) is not uncommon but has never been radiographically queried to evaluate for specific muscle anatomy. Ten subjects (9 female) were identified with paraspinal asymmetry on examination and MRI. Relative atrophy was seen diffusely in all paraspinal muscles (psoas, interspinalis, quadratus, multifidus, longissimus and ileocostalis). The quadratus, multifidus, longissimus and ileocostalis were the most asymmetric and equally involved. The interspinalis was less asymmetric, whereas the psoas was almost never asymmetric. Fatty infiltrates, consistent with radiographic myopathic degeneration, were often seen in the atrophic muscles. In 8/10 cases, the side of PD symptom onset demonstrated the greatest atrophy. Lateral postural deviation appears to result from ipsilateral paraspinal atrophy with fatty infiltration. Correlation with the most affected side suggests causality.

Original languageEnglish (US)
Pages (from-to)93-96
Number of pages4
JournalInternational Journal of Neuroscience
Issue number2
StatePublished - Feb 1 2014


  • Camptocormia
  • MRI
  • Myopathy
  • PISA
  • Paraspinal muscles
  • Parkinson's disease

ASJC Scopus subject areas

  • Neuroscience(all)


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