45 Scopus citations


A 59-year-old woman presented with acute-onset, bilateral, painless loss of vision, dysarthria, and ataxia. Ophthalmoscopy showed bilateral optic disc edema. A magnetic resonance scan of the head was normal. Chest radiography showed mediastinal adenopathy. Mediastinoscopy and biopsy identified small- cell carcinoma of the lung. An autoantibody to optic nerve and retina was demonstrated in the patient's serum. An electroretinogram was normal. The patient was diagnosed with a paraneoplastic optic neuropathy and paraneoplastic cerebellar syndrome. After treatment for her lung cancer, the patient remains stable from a visual and neurologic standpoint.

Original languageEnglish (US)
Pages (from-to)178-181
Number of pages4
JournalJournal of Neuro-Ophthalmology
Issue number3
StatePublished - 1998


  • Autoantibody
  • Paraneoplastic optic neuropathy
  • Small-cell lung carcinoma

ASJC Scopus subject areas

  • Clinical Neurology
  • Ophthalmology

Fingerprint Dive into the research topics of 'Paraneoplastic optic neuropathy and autoantibody production in small-cell carcinoma of the lung'. Together they form a unique fingerprint.

Cite this