Papillary tumor of the pineal region: Ultrastructural study of a case

Matthew D. Cykowski, Eric P. Wartchow, Gary W. Mierau, Ethan D. Stolzenberg, Mary Kay Gumerlock, Kar Ming Fung

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


Papillary tumor of the pineal region (PTPR) is a recently classified neuroepithelial tumor for which there has been little comprehensive ultrastructural study. Here, we describe the radiographic, intraoperative, histologic, immunohistochemical, and in-depth ultrastructural findings in a case of PTPR. This study corroborates that PTPR has concomitant ependymal, neuroendocrine, and secretory features, and details novel ultrastructural as well as immunohistochemical features that further this argument. Discrepancies with prior descriptions of PTPR are described, as these differences may reflect phenotypic variability in this rare tumor, and the ultrastructural features that relate to the putative ependymal origin of the entity are emphasized.

Original languageEnglish (US)
Pages (from-to)68-77
Number of pages10
JournalUltrastructural Pathology
Issue number1
StatePublished - Feb 1 2012


  • Pineal tumor
  • choroid plexus
  • ependymal
  • papillary

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Structural Biology


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