Abstract
This study examined P3a amplitude as a direct predictor of treatment success for substance dependence. Participants were 35 adults (27 men, 8 women) undergoing treatment for substance dependence at an urban residential treatment facility between October 2005 and July 2007. Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (DSM-IV-TR) criteria were used to confirm substance dependence. P3a amplitude was significantly smaller for those who dropped out of treatment. Discriminant function analysis confirmed that P3a amplitude was a robust predictor of treatment completion, more sensitive than other measures including substance abuse severity. Implications for the interpretation of P3a amplitude as an index of executive function are discussed.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 669-677 |
| Number of pages | 9 |
| Journal | Substance Use and Misuse |
| Volume | 46 |
| Issue number | 5 |
| DOIs | |
| State | Published - Mar 15 2011 |
Keywords
- P300
- P3a
- event-related potentials
- substance abuse
- treatment success
ASJC Scopus subject areas
- Medicine (miscellaneous)
- Health(social science)
- Public Health, Environmental and Occupational Health
- Psychiatry and Mental health
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