Abstract
This study examined P3a amplitude as a direct predictor of treatment success for substance dependence. Participants were 35 adults (27 men, 8 women) undergoing treatment for substance dependence at an urban residential treatment facility between October 2005 and July 2007. Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (DSM-IV-TR) criteria were used to confirm substance dependence. P3a amplitude was significantly smaller for those who dropped out of treatment. Discriminant function analysis confirmed that P3a amplitude was a robust predictor of treatment completion, more sensitive than other measures including substance abuse severity. Implications for the interpretation of P3a amplitude as an index of executive function are discussed.
Original language | English (US) |
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Pages (from-to) | 669-677 |
Number of pages | 9 |
Journal | Substance Use and Misuse |
Volume | 46 |
Issue number | 5 |
DOIs | |
State | Published - Mar 15 2011 |
Keywords
- P300
- P3a
- event-related potentials
- substance abuse
- treatment success
ASJC Scopus subject areas
- Medicine (miscellaneous)
- Health(social science)
- Public Health, Environmental and Occupational Health
- Psychiatry and Mental health