P-Bodies React to Stress and Nonsense

Ivone Bruno, Miles F. Wilkinson

Research output: Contribution to journalShort survey

32 Scopus citations

Abstract

P-bodies are specialized cytoplasmic compartments where translational repression and mRNA turnover may occur. Findings in this issue of Cell provide evidence that P-bodies are sites of "mRNA purgatory." Bhattacharyya et al. (2006) reveal that normal mRNA can be released from P-bodies and translated into protein in response to stress. Meanwhile, Sheth and Parker (2006) report that aberrant mRNAs are targeted to P-bodies to undergo rapid decay.

Original languageEnglish (US)
Pages (from-to)1036-1038
Number of pages3
JournalCell
Volume125
Issue number6
DOIs
StatePublished - Jun 2006

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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