Overcoming antiangiogenic resistance

James C. Yao, Alexandria Phan

Research output: Contribution to journalShort survey

15 Scopus citations

Abstract

The success of Drugs targeting angiogenesis is tempered by the transient duration of disease control and modest survival improvement. The very hypoxic stress produced by successful therapy may lead to upregulation of multiple pathways that promote angiogenesis and invasive behavior. Overcoming this evasive resistance may further improve outcome.

Original languageEnglish (US)
Pages (from-to)5217-5219
Number of pages3
JournalClinical Cancer Research
Volume17
Issue number16
DOIs
StatePublished - Aug 15 2011

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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