Osteoid-osteoma: Intraoperative tetracycline-fluorescence demonstration of the nidus

A. G. Ayala, J. A. Murray, M. A. Erling, A. K. Raymond

Research output: Contribution to journalArticlepeer-review

66 Scopus citations


Nine patients with a clinical and radiographic diagnosis of osteoid-osteoma received 750 to 4,000 milligrams of tetracycline preoperatively. Immediate examination of the surgically removed specimens under ultraviolet light demonstrated fluorescence of the nidus in all nine patients. Reactive and normal bone did not fluoresce. This simple technique permits quick, easy, economical, and sure verification that the nidus has been excised.

Original languageEnglish (US)
Pages (from-to)747-751
Number of pages5
JournalJournal of Bone and Joint Surgery - Series A
Issue number5
StatePublished - 1986

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine


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