Osseous metaplasia in hemangiomas of the breast: Case reports and literature review

Daniel J. Duhon, Canivan R. Anton, Jae Y. Ro, Luz A. Venta, Rose C. Anton, Mary R. Schwartz

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Unusual or prominent calcifications found on screening mammography may prompt additional radiologic and clinical work-up given the possible association with pre-malignant lesions, other high-risk lesions, or malignancies. Osseous metaplasia (OM) of the breast, also referred to as metaplastic ossification or heterotopic bone formation, is an uncommon finding that may present as radiographic calcification. There are isolated case reports of OM associated with benign or malignant tumors of the breast, as well as with a variety of non-neoplastic conditions. We report 2 cases of OM in the breast associated with a hemangioma and review the relevant literature. To the best of our knowledge, these are the first reported cases of this association in the breast.

Original languageEnglish (US)
Pages (from-to)229-234
Number of pages6
JournalJournal of Breast Cancer
Issue number2
StatePublished - 2021


  • Breast
  • Calcinosis
  • Hemangioma
  • Metaplasia

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


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