Osseous Metaplasia (Cataracta Ossea) of Lens Remnants in Chronic Uveitis—A Clinicopathologic Report

Amir Hadayer, Ahmet Özkök, Henry J. Kaplan, Shlomit Schaal

Research output: Contribution to journalLetterpeer-review

1 Scopus citations


Purpose: To describe clinically and pathologically the rare occurrence of calcification and osseous metaplasia in lens remnants in both eyes of a patient with pseudophakic chronic uveitis. Methods: We performed 25-gauge pars plana vitrectomy, removal of dislocated intraocular lens (IOL), and secondary IOL fixation in the left eye. A similar procedure was performed in the right eye with 27-gauge pars plana vitrectomy. Results: The postoperative visual acuities were 20/30 OD and 20/125 OS. Hematoxylin and eosin staining demonstrated an abundance of calcified tissue and rare osteoclasts in lacunae, compatible with osseous metaplasia (cataracta ossea). Conclusion: To our knowledge this is the first clinicopathologic report demonstrating cellular metaplasia that resulted in osseous transformation of the cortical lens remnants into bone in both eyes of a psuedophakic patient with chronic granulomatous pan uveitis of unknown etiology. The surgical technique described in the supplemental videos demonstrates an effective way of managing this complication.

Original languageEnglish (US)
Pages (from-to)133-135
Number of pages3
JournalOcular Immunology and Inflammation
Issue number1
StatePublished - Jan 2 2018


  • Bone metaplasia
  • IOL
  • cataracta ossea
  • chronic uveitis
  • cortical remnants
  • histology
  • osseous metaplasia

ASJC Scopus subject areas

  • Immunology and Allergy
  • Ophthalmology


Dive into the research topics of 'Osseous Metaplasia (Cataracta Ossea) of Lens Remnants in Chronic Uveitis—A Clinicopathologic Report'. Together they form a unique fingerprint.

Cite this