Oral Tetrahydroaminoacridine in the Treatment of Senile Dementia, Alzheimer's Type

Francis J. Pirozzolo, David S. Baskin, Andrew A. Swihart, Stanley H. Appel, N. Herrmann, J. Sadavoy, A. Steingart, Gary W. Small, J. Edward Spar, Daniel A. Plotkin, Michael Kopelman, Pierre N. Tariot, Eric D. Caine, William K. Summers, Lawrence V. Majovski, Gary M. Marsh, Kenneth Tachiki, Arthur Kling

Research output: Contribution to journalLetterpeer-review

23 Scopus citations


To the Editor: The report by Summers et a!. (Nov. 13 issue)* contains methodologic problems that render the results difficult to interpret. First, the selection of outcome variables is inappropriate. The neuropsychological assessment techniques employed included the Luria–Nebraska Neuropsychological Test, the Minnesota Multiphasic Personality Inventory, the New York University Memory Test, Wechsler's Adult Intelligence Scale, the Mini Mental State test, three psychometric tests, and a subjective measure designed by the authors. The authors do not refer to the results of any tests except the four they designed. The psychometric properties and construct validity of these psychometric scales are unknown. It…

Original languageEnglish (US)
Pages (from-to)1603-1605
Number of pages3
JournalNew England Journal of Medicine
Issue number25
StatePublished - Jun 18 1987

ASJC Scopus subject areas

  • Medicine(all)


Dive into the research topics of 'Oral Tetrahydroaminoacridine in the Treatment of Senile Dementia, Alzheimer's Type'. Together they form a unique fingerprint.

Cite this