@article{87c0ddf6cc5c4d47a6843f186e2f6d26,
title = "Optical clearing for OCT image enhancement and in-depth monitoring of molecular diffusion",
abstract = "In this paper, we overview the basic principles, recent results, advantages, limitations, and future of the optical clearing method in application to many fields of biology and medicine. We also discuss the possibility of noninvasive assessment of molecular diffusion in tissues using the optical coherence tomography technique. Issues of safety and toxicity of application of different endogenous and exogenous molecules to tissues are outlined.",
keywords = "Molecular diffusion, optical clearing, optical coherence tomography",
author = "Larin, {Kirill V.} and Ghosn, {Mohamad G.} and Bashkatov, {Alexey N.} and Genina, {Elina A.} and Trunina, {Natalia A.} and Tuchin, {Valery V.}",
note = "Funding Information: Manuscript received October 26, 2011; revised December 15, 2011; accepted December 15, 2011. Date of publication December 27, 2011; date of current version June 1, 2012. This work was supported in part by the Institute of Biomedical Imaging Sciences under Grant IBIS-97708, the NIH/NHLBI under Grant T32-HL07812, the AHA under Grant 11POST7430064, the Civilian Research and Development Foundation under Grant RUB1-2932-SR-08, and the National Science Foundation under Grant CMMI-0900743; in part by the Russian Foundation for Basic Research under Grant 10-07-00526-a; in part by the Grant 224014 PHOTONICS4LIFE of FP7-ICT-2007-2; in part by the Projects 1.4.09, 2.1.1/4989, and 2.2.1.1/2950 of the RF Ministry of Education and Science; in part by the RF Governmental Contracts 02.740.11.0484, 02.740.11.0770, and 02.740.11.0879; and in part by the FiDiPro, TEKES Program (40111/11), Finland.",
year = "2012",
doi = "10.1109/JSTQE.2011.2181991",
language = "English (US)",
volume = "18",
pages = "1244--1259",
journal = "IEEE Journal on Selected Topics in Quantum Electronics",
issn = "1077-260X",
publisher = "Institute of Electrical and Electronics Engineers Inc.",
number = "3",
}