TY - JOUR
T1 - Optic Pit Maculopathy
T2 - Clinical Features and Management Options
AU - Iyer, Prashanth G.
AU - Flynn, Harry W.
AU - Fan, Kenneth C.
AU - Berrocal, Audina M.
AU - Goldhardt, Raquel
N1 - Publisher Copyright:
© 2021, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
PY - 2021/12
Y1 - 2021/12
N2 - Purpose of Review: In this article, we review the pathogenesis, clinical features, imaging modalities, and latest management options for optic pit maculopathy (OPM). Recent Findings: The pathogenesis of OPM remains to be unclear, but imaging tools such as optical coherence tomography (OCT) and OCT angiography are enhancing our knowledge. Observation continues to be the best management strategy for patients with good visual acuity, and many cases have demonstrated spontaneous resolution. For more advanced, progressive vision loss, treatment options involving vitrectomy can be considered and discussed with the patient. Supplementary techniques to vitrectomy have been reported in small studies with relative success such as glial tissue peeling, inverted internal limiting membrane flap, optic pit plugging, and retinal fenestration. Summary: While there are multiple treatment options available for OPM, there is no consensus on the technique and surgical timing. Individual patient factors and the risks-benefits of treatment must be taken into account in guiding management. Larger clinical trials will further assist in decision-making for treating OPM.
AB - Purpose of Review: In this article, we review the pathogenesis, clinical features, imaging modalities, and latest management options for optic pit maculopathy (OPM). Recent Findings: The pathogenesis of OPM remains to be unclear, but imaging tools such as optical coherence tomography (OCT) and OCT angiography are enhancing our knowledge. Observation continues to be the best management strategy for patients with good visual acuity, and many cases have demonstrated spontaneous resolution. For more advanced, progressive vision loss, treatment options involving vitrectomy can be considered and discussed with the patient. Supplementary techniques to vitrectomy have been reported in small studies with relative success such as glial tissue peeling, inverted internal limiting membrane flap, optic pit plugging, and retinal fenestration. Summary: While there are multiple treatment options available for OPM, there is no consensus on the technique and surgical timing. Individual patient factors and the risks-benefits of treatment must be taken into account in guiding management. Larger clinical trials will further assist in decision-making for treating OPM.
KW - Congenital optic pit
KW - Lamina cribosa
KW - Maculopathy
KW - Optic pit
KW - Optic pit maculopathy
KW - Pars plana vitrectomy
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U2 - 10.1007/s40135-021-00274-0
DO - 10.1007/s40135-021-00274-0
M3 - Review article
AN - SCOPUS:85116410674
SN - 2167-4868
VL - 9
SP - 158
EP - 167
JO - Current Ophthalmology Reports
JF - Current Ophthalmology Reports
IS - 4
ER -