Once upon a Cataract Surgeon

Roma P. Patel; John Volpi; Andrew G. Lee; Jason J.S. Barton

doi:10.1016/j.survophthal.2011.05.002

Once upon a Cataract Surgeon

Roma P. Patel, John Volpi, Andrew G. Lee, Jason J.S. Barton

Research output: Contribution to journal › Article › peer-review

Abstract

A 60-year-old man presented with diplopia and neurocognitive deficits, which progressed rapidly over several months. Magnetic resonance imaging of the head revealed bilateral signal abnormalities and diffusion-weighted imaging restriction in bilateral basal ganglia, thalami, mesial temporal regions, and periaqueductal gray matter. Cerebrospinal fluid analysis was positive for 14-3-3 and tau proteins. The patient developed progressive neurocognitive decline followed by sleep disturbance and myoclonic jerking consistent with probable Creutzfeldt-Jakob disease.

Original language	English (US)
Pages (from-to)	379-385
Number of pages	7
Journal	Survey of Ophthalmology
Volume	57
Issue number	4
DOIs	https://doi.org/10.1016/j.survophthal.2011.05.002
State	Published - Jul 2012

Keywords

14-3-3
Creutzfeldt-Jakob disease
Diffusion-weighted imaging
Diplopia
Neurocognitive

ASJC Scopus subject areas

Ophthalmology

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10.1016/j.survophthal.2011.05.002

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title = "Once upon a Cataract Surgeon",

abstract = "A 60-year-old man presented with diplopia and neurocognitive deficits, which progressed rapidly over several months. Magnetic resonance imaging of the head revealed bilateral signal abnormalities and diffusion-weighted imaging restriction in bilateral basal ganglia, thalami, mesial temporal regions, and periaqueductal gray matter. Cerebrospinal fluid analysis was positive for 14-3-3 and tau proteins. The patient developed progressive neurocognitive decline followed by sleep disturbance and myoclonic jerking consistent with probable Creutzfeldt-Jakob disease.",

keywords = "14-3-3, Creutzfeldt-Jakob disease, Diffusion-weighted imaging, Diplopia, Neurocognitive",

author = "Patel, {Roma P.} and John Volpi and Lee, {Andrew G.} and Barton, {Jason J.S.}",

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AU - Volpi, John

AU - Lee, Andrew G.

AU - Barton, Jason J.S.

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AB - A 60-year-old man presented with diplopia and neurocognitive deficits, which progressed rapidly over several months. Magnetic resonance imaging of the head revealed bilateral signal abnormalities and diffusion-weighted imaging restriction in bilateral basal ganglia, thalami, mesial temporal regions, and periaqueductal gray matter. Cerebrospinal fluid analysis was positive for 14-3-3 and tau proteins. The patient developed progressive neurocognitive decline followed by sleep disturbance and myoclonic jerking consistent with probable Creutzfeldt-Jakob disease.

KW - 14-3-3

KW - Creutzfeldt-Jakob disease

KW - Diffusion-weighted imaging

KW - Diplopia

KW - Neurocognitive

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Once upon a Cataract Surgeon

Abstract

Keywords

ASJC Scopus subject areas

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