On the Hepatic Sulphurylating Activity in Male Pseudohermaphroditic Rats

Jan Åke Gustafsson, Jan Carlstedt-Duke, Allen S. Goldman

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

The sulphurylation of [1,2-3H]-deoxycorticosterone was studied in the 105,000g supernatant fluid obtained from liver homogenates of intact and castrated male pseudohermaphroditic, normal female, and normal male rats with and without treatment with steroid hormones. Male pseudohermaphroditic and normal female rats had similar sulphurylating activities which were higher than that of normal male rats. It was shown that the sulphurylating activity in male pseudohermaphroditic and normal female rats is normally regulated mainly by nongonadal factors and that the sulphurylating activity in normal male rats is suppressed by testicular androgens.

Original languageEnglish (US)
Pages (from-to)908-911
Number of pages4
JournalProceedings of the Society for Experimental Biology and Medicine
Volume145
Issue number3
DOIs
StatePublished - Mar 1974

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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