Abstract
Olmesartan-induced enteropathy mimics celiac disease clinically and pathologically. As in celiac disease, the pathologic findings are villous atrophy and increased intraepithelial lymphocytes. Clinical presentation of olmesartan-induced enteropathy includes diarrhea, weight loss, and nausea. In contrast to celiac disease, tissue transglutaminase is not elevated and there is no response to a gluten-free diet. Including this entity in the differential diagnosis of sprue-like enteropathy is critical for its early diagnosis since replacing olmesartan with an alternative antihypertensive drug can simplify the diagnostic workup and provide both clinical and histologic improvement.
Original language | English (US) |
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Pages (from-to) | 230-232 |
Number of pages | 3 |
Journal | Methodist DeBakey cardiovascular journal |
Volume | 12 |
Issue number | 4 |
DOIs | |
State | Published - Oct 1 2016 |
Keywords
- celiac disease
- diarrhea
- olmesartan-induced enteropathy
ASJC Scopus subject areas
- General Medicine