Metastatic cancer patients represent a highly heterogeneous cohort with widely differing prognoses. The application of local, metastasis-directed therapies is becoming increasingly appealing, but controversies regarding patients most likely to benefit from these interventions remain. This chapter aims to evaluate the phenomenon of the oligometastatic state, rationales for utilizing local therapy (surgical and radiotherapeutic), as well as summarize the available evidence thereof. A discussion on interactions of local therapy with immunotherapy, ongoing clinical trials, and optimal patient selection is also conducted.

Original languageEnglish (US)
Title of host publicationMedical Radiology
Number of pages10
StateE-pub ahead of print - Feb 19 2019

Publication series

NameMedical Radiology
ISSN (Print)0942-5373
ISSN (Electronic)2197-4187

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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