Oestrogen Receptors

Rodrigo P.A. Barros; Jan Åke Gustafsson

doi:10.1042/bio03102008

Oestrogen Receptors

Rodrigo P.A. Barros, Jan Åke Gustafsson

Houston Methodist

Research output: Contribution to journal › Article › peer-review

Abstract

The birth of nuclear receptors took place at the end of the 1950s when Elwood Jensen discovered specific binding of tritium-labelled oestradiol-17β in the uterus, a known target of oestrogens. Over the following years, Jensen and collaborators, e.g. Jacobsen and Gorski, identified the oestradiolconcentrating mechanism as a high-affinity low-capacity soluble receptor which was termed the ER (oestrogen receptor)1

Original language	English (US)
Pages (from-to)	8-11
Number of pages	4
Journal	Biochemist
Volume	31
Issue number	2
DOIs	https://doi.org/10.1042/bio03102008
State	Published - 2009

Keywords

DNA
insulin resistance
ligand
nuclear
oestrogen
receptor
steroid

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

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10.1042/bio03102008

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KW - receptor

KW - steroid

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Oestrogen Receptors

Abstract

Keywords

ASJC Scopus subject areas

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