Ocular and orbital complications of intraarterial cisplatin: A case report

Helen M. Wu; Andrew G. Lee; Daniel E. Lehane; T. Linda Chi; Richard Alan Lewis

doi:10.1097/00041327-199709000-00010

Ocular and orbital complications of intraarterial cisplatin: A case report

Helen M. Wu, Andrew G. Lee, Daniel E. Lehane, T. Linda Chi, Richard Alan Lewis

Research output: Contribution to journal › Article › peer-review

27 Scopus citations

Abstract

Despite advances in neurosurgery, radiation oncology, and chemotherapy, the prognosis for glioblastoma multiforme remains poor, with a median survival time of 11-12 months. Cisplatin (cis-diamminedichlorideplatinum II) is one treatment for glioblastoma multiforme. Higher response rates have been achieved by intraarterial (i.a.) infusion than by systemic infusion of this agent. Cisplatin therapy may cause neurologic complications, and i.a. delivery has been reported to cause ocular toxicity. We report a patient who experienced intraorbital and intraocular toxicity following supraophthalmic i.a. injection of cisplatin.

Original language	English (US)
Pages (from-to)	195-198
Number of pages	4
Journal	Journal of Neuro-Ophthalmology
Volume	17
Issue number	3
DOIs	https://doi.org/10.1097/00041327-199709000-00010
State	Published - 1997

Keywords

Cisplatin
Intra-arterial

ASJC Scopus subject areas

Ophthalmology
Clinical Neurology

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10.1097/00041327-199709000-00010

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title = "Ocular and orbital complications of intraarterial cisplatin: A case report",

abstract = "Despite advances in neurosurgery, radiation oncology, and chemotherapy, the prognosis for glioblastoma multiforme remains poor, with a median survival time of 11-12 months. Cisplatin (cis-diamminedichlorideplatinum II) is one treatment for glioblastoma multiforme. Higher response rates have been achieved by intraarterial (i.a.) infusion than by systemic infusion of this agent. Cisplatin therapy may cause neurologic complications, and i.a. delivery has been reported to cause ocular toxicity. We report a patient who experienced intraorbital and intraocular toxicity following supraophthalmic i.a. injection of cisplatin.",

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T1 - Ocular and orbital complications of intraarterial cisplatin

T2 - A case report

AU - Wu, Helen M.

AU - Lee, Andrew G.

AU - Lehane, Daniel E.

AU - Linda Chi, T.

AU - Lewis, Richard Alan

PY - 1997

Y1 - 1997

N2 - Despite advances in neurosurgery, radiation oncology, and chemotherapy, the prognosis for glioblastoma multiforme remains poor, with a median survival time of 11-12 months. Cisplatin (cis-diamminedichlorideplatinum II) is one treatment for glioblastoma multiforme. Higher response rates have been achieved by intraarterial (i.a.) infusion than by systemic infusion of this agent. Cisplatin therapy may cause neurologic complications, and i.a. delivery has been reported to cause ocular toxicity. We report a patient who experienced intraorbital and intraocular toxicity following supraophthalmic i.a. injection of cisplatin.

AB - Despite advances in neurosurgery, radiation oncology, and chemotherapy, the prognosis for glioblastoma multiforme remains poor, with a median survival time of 11-12 months. Cisplatin (cis-diamminedichlorideplatinum II) is one treatment for glioblastoma multiforme. Higher response rates have been achieved by intraarterial (i.a.) infusion than by systemic infusion of this agent. Cisplatin therapy may cause neurologic complications, and i.a. delivery has been reported to cause ocular toxicity. We report a patient who experienced intraorbital and intraocular toxicity following supraophthalmic i.a. injection of cisplatin.

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Ocular and orbital complications of intraarterial cisplatin: A case report

Abstract

Keywords

ASJC Scopus subject areas

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