Nucleus-mitochondria positive feedback loop formed by ERK5 S496 phosphorylation-mediated poly (ADP-ribose) polymerase activation provokes persistent pro-inflammatory senescent phenotype and accelerates coronary atherosclerosis after chemo-radiation

Sivareddy Kotla, Aijun Zhang, Masaki Imanishi, Kyung Ae Ko, Steven H Lin, Young Jin Gi, Margie Moczygemba, Sevinj Isgandarova, Keri L Schadler, Caroline Chung, Sarah A Milgrom, Jose Banchs, Syed Wamique Yusuf, Diana N Amaya, Huifang Guo, Tamlyn N Thomas, Ying H Shen, Anita Deswal, Joerg Herrmann, Eugenie S KleinermanMark L Entman, John P Cooke, Giovanni Schifitto, Sanjay B Maggirwar, Elena McBeath, Anisha A Gupte, Sunil Krishnan, Zarana S Patel, Yisang Yoon, Jared K Burks, Keigi Fujiwara, Paul S Brookes, Nhat-Tu Le, Dale J Hamilton, Jun-Ichi Abe

Research output: Contribution to journalArticlepeer-review

Fingerprint

Dive into the research topics of 'Nucleus-mitochondria positive feedback loop formed by ERK5 S496 phosphorylation-mediated poly (ADP-ribose) polymerase activation provokes persistent pro-inflammatory senescent phenotype and accelerates coronary atherosclerosis after chemo-radiation'. Together they form a unique fingerprint.

Medicine & Life Sciences

Chemistry