Kärnreceptorer hos människa, fluga och mask ger ökad sjukdomsförståelse.

Translated title of the contribution: Nuclear receptors in man, fly and worm provide greater understanding of disease

Eva Enmark, Jan-Ake Gustafsson

Research output: Contribution to journalReview article

1 Scopus citations

Abstract

Recently the complete genomic sequences for three very different multicellular organisms have been published, from one nematode (Caenorhabditis elegans), one fly (Drosophila melanogaster) and human (Homo sapiens). Of course, this means a breakthrough in many ways for biological research. Summarised in this article are the findings made using these genomic sequences regarding the protein family of nuclear receptors. This is a group of transcription factors involved in many important biological processes, i.e. regulation of cholesterol homeostasis and fertility; classical members of this protein family are, amongst others, the receptors for estradiol and progesterone.

Translated title of the contributionNuclear receptors in man, fly and worm provide greater understanding of disease
Original languageSwedish
Pages (from-to)1186-1190
Number of pages5
JournalLäkartidningen
Volume99
Issue number11
StatePublished - Jan 1 2002

ASJC Scopus subject areas

  • Medicine(all)

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