Nuclear receptors in analytics - a fruitful joint venture or a wasteful futility?

Peter Fechner, Günter Gauglitz, Jan Åke Gustafsson

    Research output: Contribution to journalReview articlepeer-review

    9 Scopus citations

    Abstract

    This review compares analytical techniques, approaches and assay formats employing nuclear receptors (NRs). We give a brief overview of the analytically interesting properties of NRs in general, and we discuss the possible benefits for classical analytical techniques (e.g., mass spectrometry or nuclear magnetic resonance) and rather new analytical methods (e.g., biosensors or in silico approaches). We especially highlight the combination of analytical methods together with their enhancement using NRs and their possible fields of application in future.

    Original languageEnglish (US)
    Pages (from-to)297-305
    Number of pages9
    JournalTrAC - Trends in Analytical Chemistry
    Volume29
    Issue number4
    DOIs
    StatePublished - Apr 2010

    Keywords

    • Analysis
    • Assay
    • Biosensor
    • Effect-directed analysis
    • Endocrine disruptor
    • In silico analysis
    • Mass spectrometry
    • Nuclear magnetic resonance
    • Nuclear receptor
    • Screening

    ASJC Scopus subject areas

    • Analytical Chemistry
    • Spectroscopy
    • Environmental Chemistry

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