Novel dose escalation to predict treatment with hydroxyurea (NDEPTH): A randomized controlled trial of a dose-prediction equation to determine maximum tolerated dose of hydroxyurea in pediatric sickle cell disease

Alex George, Bogdan Dinu, Norma Estrada, Charles G. Minard, Richard Hurwitz, Donald H. Mahoney, Amber M. Yates, Mary Vaughan, Alaundra Carmouche, Gladstone Airewele, Susan E. Kirk, Titilope Fasipe, Precious Uwaezuoke, Russell E. Ware

Research output: Contribution to journalLetterpeer-review

4 Scopus citations
Original languageEnglish (US)
Pages (from-to)E242-E244
JournalAmerican Journal of Hematology
Issue number9
StatePublished - Sep 1 2020


  • Adolescent
  • Anemia, Sickle Cell/drug therapy
  • Child
  • Female
  • Humans
  • Hydroxyurea/administration & dosage
  • Male
  • Maximum Tolerated Dose

ASJC Scopus subject areas

  • Hematology

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