Non-Neural (S-100 Negative) Bronchial Granular Cell Tumor Causing Acute Respiratory Failure

Stephanie Y. Chen, Arhanti Sadanand, Patrick A. Dillon, Mai He, Louis P. Dehner, David S. Leonard

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


Introduction: Endobronchial granular cell tumors are uncommon in the pediatric population. Case report: A 9-year-old female presented with respiratory failure due to an endobronchial tumor. After debulking and diagnosis, she underwent thoracotomy with right upper lobe resection and bronchoplasty. Pathology demonstrated an endobronchial S-100 negative granular cell tumor, which to our knowledge, is the first such report in the literature. Conclusion: Endobronchial granular cell tumors may cause obstructive respiratory failure, are amenable to surgery, and may be S-100 negative.

Original languageEnglish (US)
Pages (from-to)85-89
Number of pages5
JournalFetal and Pediatric Pathology
Issue number1
StatePublished - Jan 2 2020


  • alveolar soft part sarcoma
  • endobronchial mass
  • granular cell tumor
  • S-100 protein

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Pathology and Forensic Medicine


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