@article{b60f29047d3748bdbc65ee51dc2f4cf2,
title = "No Evidence for Association between the Polymorphism in the 3′ Untranslated Region of Interleukin-12B and Human Susceptibility to Tuberculosis",
abstract = "Interleukin (IL)-12 plays a pivotal role in cell-mediated immunity to Mycobacterium tuberculosis infection. We tested the association between a biallelic single-nucleotide polymorphism in the 3′ untranslated region (UTR) of IL-12B and human susceptibility to tuberculosis (TB), in a population-based case-control study of adult patients with TB from 2 ethnicities, African American and white, and in a family-based transmission/disequilibrium study of 60 informative families with at least 1 pediatric patient with TB and 1 heterozygous parent. Our results suggest that IL-12B 3′ UTR has no effect or has a negligible effect on human susceptibility to TB.",
author = "Xin Ma and Reich, {Robert A.} and Omar Gonzalez and Xi Pan and Fothergill, {Amanda K.} and Starke, {Jeffery R.} and Teeter, {Larry D.} and Musser, {James M.} and Graviss, {Edward A.}",
note = "Funding Information: Received 17 March 2003; accepted 30 April 2003; electronically published 26 September 2003. Financial support: National Institute of Allergy and Infectious Diseases, National Institutes of Health (contracts N01-AO-02738 and AI 41168). The novel single-nucleotide polymorphism (SNP) reported in this study has been deposited in the SNP database of the National Center for Biotechnology Information (assay identification number [ss#] 4480616). Reprints or correspondence: Dr. Edward A. Graviss, Dept. of Pathology (209E), Baylor College of Medicine, One Baylor Plaza, Houston, TX, 77030 (egraviss@bcm.tmc.edu). Copyright: Copyright 2008 Elsevier B.V., All rights reserved.",
year = "2003",
month = oct,
day = "15",
doi = "10.1086/378674",
language = "English (US)",
volume = "188",
pages = "1116--1118",
journal = "Journal of Infectious Diseases",
issn = "0022-1899",
publisher = "Oxford University Press",
number = "8",
}