Nitric oxide-generating L-cysteine-grafted graphene film as a blood-contacting biomaterial

Zhen Du, Ruixia Dou, Mian Zu, Xueying Liu, Wenyan Yin, Yuliang Zhao, Jingbo Chen, Liang Yan, Zhanjun Gu

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

By using polyethylenimine molecules as the linker, l-cysteine was immobilized onto graphene nanosheets, endowing the biocompatible l-cysteine-functionalized graphene film with the ability for catalytic decomposition of exogenous or endogenous donors to generate nitric oxide, and thus inhibiting the platelet activation and aggregation and reducing platelet adhesion.

Original languageEnglish (US)
Pages (from-to)938-942
Number of pages5
JournalBiomaterials Science
Volume4
Issue number6
DOIs
StatePublished - Jun 2016

ASJC Scopus subject areas

  • Biomedical Engineering
  • Materials Science(all)

Fingerprint

Dive into the research topics of 'Nitric oxide-generating L-cysteine-grafted graphene film as a blood-contacting biomaterial'. Together they form a unique fingerprint.

Cite this