Abstract
The iodine-magnesium exchange reaction allows the preparation of polyfunctional aryl, heteroaryl, or alkenyl magnesium reagents at low temperature. These reagents display the typical reactivity of Grignard compounds and undergo various copper-catalyzed reactions such as allylation or 1,4-addition. Using this halogen -metal exchange reaction, it was possible to generate polyfunctional magnesium reagents on the solid phase.
Original language | English (US) |
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Pages (from-to) | 767-770 |
Number of pages | 4 |
Journal | Chemistry - A European Journal |
Volume | 6 |
Issue number | 5 |
DOIs | |
State | Published - Mar 3 2000 |
Keywords
- Catalysis
- Copper
- Cyclizations
- Hetero-cycles
- Magnesium
- Solid-phase synthesis
ASJC Scopus subject areas
- Catalysis
- General Chemistry
- Organic Chemistry