New-Onset Seizures in Three COVID-19 Patients: A Case Series

Farhan Mithani, Meryim Poursheykhi, Brandy Ma, Robert G. Smith, Steven H. Hsu, Deepa Gotur

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


Neurological manifestations of coronavirus disease 2019 most commonly present in severe cases and range from mild complications, such as headache and dizziness, to severe complications, such as encephalopathy and acute cerebrovascular disease. Seizures, however, are an underreported neurological manifestation of this disease. We present three critically ill coronavirus disease 2019 patients with EEG monitoring who developed new-onset seizures and encephalopathy up to three-and-a-half weeks after symptom onset. There are several speculated etiologies for the development of new-onset seizures; however, the pathogenic mechanism remains unknown. Testing of coronavirus disease 2019 in the cerebrospinal fluid in addition to extensive research on neurological manifestations is warranted.

Original languageEnglish (US)
Pages (from-to)E5-E10
JournalJournal of Clinical Neurophysiology
Issue number2
StatePublished - Mar 1 2021


  • Adult
  • Aged
  • Brain Diseases/virology
  • COVID-19/complications
  • Dizziness/virology
  • Female
  • Headache/virology
  • Humans
  • Male
  • Middle Aged
  • SARS-CoV-2
  • Seizures/virology

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology
  • Physiology (medical)
  • Physiology


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