New ligands that promote cross-coupling reactions between aryl halides and unactivated arenes

Yatao Qiu, Yanghan Liu, Kai Yang, Wenkun Hong, Zheng Li, Zhaoyang Wang, Zhiyi Yao, Sheng Jiang

Research output: Contribution to journalArticle

119 Scopus citations

Abstract

Several ligands were designed to promote transition-metal-free cross-coupling reactions of aryl halides with benzene derivatives. Among the systems probed, quinoline-1-amino-2-carboxylic acid was found to serve as an excellent catalyst for cross-coupling between aryl halides and unactivated benzene. Reactions using this inexpensive catalytic system displayed a high functional group tolerance as well as excellent chemoselectivities.

Original languageEnglish (US)
Pages (from-to)3556-3559
Number of pages4
JournalOrganic Letters
Volume13
Issue number14
DOIs
StatePublished - Jul 15 2011

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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