New insights from chemical biology: Molecular basis of transmission, diagnosis, and therapy of SARS-CoV-2

Zilong Zhao, Yaling Wang, Liping Qiu, Ting Fu, Yu Yang, Ruizi Peng, Mengyu Guo, Lichun Mao, Chunying Chen, Yuliang Zhao, Weihong Tan

Research output: Contribution to journalReview articlepeer-review

15 Scopus citations

Abstract

Coronavirus disease 2019 (COVID-19) is caused by a novel strain of coronavirus, designated as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It has caused a global pandemic rapidly sweeping across all countries, bringing social and economic hardship to millions. Most countries have implemented early warning measures to detect, isolate, and treat patients infected with SARS-CoV-2. This minireview summarizes some of those steps, in particular, testing methods and drug development in the context of chemical biology, and discusses the molecular basis of COVID-19’s virulent transmissibility.

Original languageEnglish (US)
Pages (from-to)1501-1528
Number of pages28
JournalCCS Chemistry
Volume3
Issue number1
DOIs
StatePublished - Jan 2021

Keywords

  • COVID-19
  • Diagnosis
  • SARS-CoV-2
  • Therapy
  • Transmission

ASJC Scopus subject areas

  • Chemistry(all)

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