TY - JOUR
T1 - New developments in microarray technology
AU - Blohm, Dietmar H.
AU - Guiseppi-Elie, Anthony
N1 - Funding Information:
We thank M Adler and A Schaffrath for their help in preparing the manuscript, R Amann, T Schulz and M Wolf for critically reading it, and A Jung and G Gauglitz for providing unpublished information including Fig. 3 . Support for Dietmar Blohm comes from Land Bremen and BMBF (contract AZ 118333A) and for Anthony Guiseppe-Elie from VCU Center for Bioelectronics, Biosensors and Biochips (CIT IO-99-010).
PY - 2001/9/7
Y1 - 2001/9/7
N2 - Microarrays have emerged as indispensable research tools for gene expression profiling and mutation analysis. New classification of cancer subtypes, dissecting the yeast metabolism and large-scale genotyping of human single nucleotide polymorphisms are important results being obtained with this technique. Realizing the microsphere-based massively parallel signature sequencing technique as fluid microarrays, building new types of protein arrays and constructing miniaturized flow-through systems, which can potentially take this technology from the research bench into industrial, clinical and other routine applications, exemplify the intense developments that are now ongoing in this field.
AB - Microarrays have emerged as indispensable research tools for gene expression profiling and mutation analysis. New classification of cancer subtypes, dissecting the yeast metabolism and large-scale genotyping of human single nucleotide polymorphisms are important results being obtained with this technique. Realizing the microsphere-based massively parallel signature sequencing technique as fluid microarrays, building new types of protein arrays and constructing miniaturized flow-through systems, which can potentially take this technology from the research bench into industrial, clinical and other routine applications, exemplify the intense developments that are now ongoing in this field.
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U2 - 10.1016/S0958-1669(00)00175-0
DO - 10.1016/S0958-1669(00)00175-0
M3 - Review article
C2 - 11167071
AN - SCOPUS:0035823072
SN - 0958-1669
VL - 12
SP - 41
EP - 47
JO - Current Opinion in Biotechnology
JF - Current Opinion in Biotechnology
IS - 1
ER -