Neuroticism associated with neural activation patterns to positive stimuli

Jennifer C. Britton, Shao Hsuan Ho, Stephan F. Taylor, Israel Liberzon

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


Relationships between neuroticism and neural activation to salient emotional stimuli were examined in three magnetic resonance imaging studies in which participants viewed International Affective Picture System pictures or emotional films. Neuroticism directly correlated with dorsomedial prefrontal cortex activation in response to positive stimuli. Dorsomedial prefrontal cortex correlations may reflect increased self-association in individuals with high neuroticism.

Original languageEnglish (US)
Pages (from-to)263-267
Number of pages5
JournalPsychiatry Research - Neuroimaging
Issue number3
StatePublished - Dec 15 2007


  • Medial prefrontal cortex
  • NEO-PI-R
  • fMRI

ASJC Scopus subject areas

  • Neuroscience (miscellaneous)
  • Radiology Nuclear Medicine and imaging
  • Psychiatry and Mental health


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