TY - CHAP
T1 - Neurosurgical Management of high grade gliomas
AU - Rostomily, Robert C.
AU - Spence, Alexander M.
AU - Silbergeld, Daniel L.
PY - 2004
Y1 - 2004
N2 - High-grade gliomas include malignant variants of tumors derived from astrocytic and oligodendropheral cell lines. These tumors demonstrate invasive behavior, are rapidly growing and are usually characterized by contrast enhancement and edema on MR or CT neuroimaging. Management includes either biopsy or surgical resection followed by radiotherapy in the majority of cases. Additional adjuvant chemotherapy is also a treatment consideration. Despite advances in management, the prognosis remains poor, with few patients surviving beyond 2–3 years.
AB - High-grade gliomas include malignant variants of tumors derived from astrocytic and oligodendropheral cell lines. These tumors demonstrate invasive behavior, are rapidly growing and are usually characterized by contrast enhancement and edema on MR or CT neuroimaging. Management includes either biopsy or surgical resection followed by radiotherapy in the majority of cases. Additional adjuvant chemotherapy is also a treatment consideration. Despite advances in management, the prognosis remains poor, with few patients surviving beyond 2–3 years.
UR - https://link.springer.com/chapter/10.1007/1-84628-051-6_10
U2 - 10.1007/1-84628-051-6_10
DO - 10.1007/1-84628-051-6_10
M3 - Chapter (peer-reviewed)
SN - 978-1-85233-522-9
T3 - Springer Specialist Surgery Series
SP - 167
EP - 186
BT - International Practices in Neurosurgery
PB - Springer-Verlag London Ltd
CY - London
ER -