Neuroleptic malignant syndrome: Successful treatment with dantrolene and bromocriptine

Jerome E. Granato, Barney J. Stern, Alan Ringel, Amin H. Karim, Allan Krumholz, Joseph Coyle, Sam Adler

Research output: Contribution to journalArticlepeer-review

111 Scopus citations


A patient with chronic schizophrenia treated with fluphenazine developed neuroleptic malignant syndrome, characterized by fever, obtundation, rigidity, and tremulousness. Hyperthermia and elevated serum creatine kinase were successfully corrected by parenteral treatment with dantrolene. Obtundation, rigidity, and tremulousness responded to high doses of bromocriptine.

Original languageEnglish (US)
Pages (from-to)89-90
Number of pages2
JournalAnnals of Neurology
Issue number1
StatePublished - Jul 1983

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology


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