Natural history of pulmonary scar cancers clinical and pathologic implications

Philip T. Cagle, Stephen D. Cohle, S. Donald Greenberg

Research output: Contribution to journalArticlepeer-review

32 Scopus citations


Twenty-two cases of resected pulmonary scar cancers in which 10 year or greater follow-up could be obtained were evaluated to determine morphologic and clinical criteria which would predict long-term survival and elucidate the cause and effect relationship of the scar to the cancer. Maturity of the scar was found to be an important criterion in predicting long-term survival. Of patients with tumors ≤ 3 cm, only one of six with an early scar died with cancer, whereas four of eight patients with advanced scars died with cancer. All tumors > 3 cm had advanced scars and five of eight patients in this category died with cancer. These findings support the concept that the scar develops secondary to the cancer and that the maturity of the scar can be used as a prognostic criterion in resected tumors.

Original languageEnglish (US)
Pages (from-to)2031-2035
Number of pages5
Issue number8
StatePublished - Oct 15 1985

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


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