Nanoshell-based substrates for surface enhanced spectroscopic detection of biomolecules

Carly S Levin; Janardan Kundu; Aoune Barhoumi; Naomi J. Halas

doi:10.1039/b909080k

Nanoshell-based substrates for surface enhanced spectroscopic detection of biomolecules

Carly S Levin, Janardan Kundu, Aoune Barhoumi, Naomi J. Halas

Research output: Contribution to journal › Article

46 Scopus citations

Abstract

Nanoshells are optically tunable core-shell nanostructures with demonstrated uses in surface enhanced spectroscopies. Based on their ability to support surface plasmons, which give rise to strongly enhanced electromagnetic fields at their surface, nanoshells provide simple, scalable, high-quality substrates. In this article, we outline the development and use of nanoshell-based substrates for direct, spectroscopic detection of biomolecules. Recent advances in the use of these nanostructures lead to improved spectroscopic quality, selectivity, and reproducibility.

Original language	English (US)
Pages (from-to)	1745-50
Number of pages	6
Journal	Analyst
Volume	134
Issue number	9
DOIs	https://doi.org/10.1039/b909080k
State	Published - Sep 2009

Keywords

DNA
Lipid Bilayers
Nanoshells
Peptides
Proteins
Spectrum Analysis, Raman
Surface Plasmon Resonance
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
Review

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10.1039/b909080k

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title = "Nanoshell-based substrates for surface enhanced spectroscopic detection of biomolecules",

abstract = "Nanoshells are optically tunable core-shell nanostructures with demonstrated uses in surface enhanced spectroscopies. Based on their ability to support surface plasmons, which give rise to strongly enhanced electromagnetic fields at their surface, nanoshells provide simple, scalable, high-quality substrates. In this article, we outline the development and use of nanoshell-based substrates for direct, spectroscopic detection of biomolecules. Recent advances in the use of these nanostructures lead to improved spectroscopic quality, selectivity, and reproducibility.",

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author = "Levin, {Carly S} and Janardan Kundu and Aoune Barhoumi and Halas, {Naomi J.}",

year = "2009",

month = sep,

doi = "10.1039/b909080k",

language = "English (US)",

volume = "134",

pages = "1745--50",

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AU - Kundu, Janardan

AU - Barhoumi, Aoune

AU - Halas, Naomi J.

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AB - Nanoshells are optically tunable core-shell nanostructures with demonstrated uses in surface enhanced spectroscopies. Based on their ability to support surface plasmons, which give rise to strongly enhanced electromagnetic fields at their surface, nanoshells provide simple, scalable, high-quality substrates. In this article, we outline the development and use of nanoshell-based substrates for direct, spectroscopic detection of biomolecules. Recent advances in the use of these nanostructures lead to improved spectroscopic quality, selectivity, and reproducibility.

KW - DNA

KW - Lipid Bilayers

KW - Nanoshells

KW - Peptides

KW - Proteins

KW - Spectrum Analysis, Raman

KW - Surface Plasmon Resonance

KW - Journal Article

KW - Research Support, N.I.H., Extramural

KW - Research Support, Non-U.S. Gov't

KW - Research Support, U.S. Gov't, Non-P.H.S.

KW - Review

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DO - 10.1039/b909080k

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JO - Analyst

JF - Analyst

SN - 0003-2654

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