Abstract
We present "Print-and-Peel", a high-throughput method to generate multicomponent biomolecular arrays with sub-100 nm nanoscale feature width. An inkjet printer is first aligned to a parylene template containing nanoscale openings. After printing, the parylene is peeled off to reveal uniformly patterned nanoscale features, despite the imperfect morphologies of the original inkjet spots. We further patterned combinatorial nanoarrays by performing a second print-run superimposed over the first, thereby extending the multiplexing capability of the technique.
Original language | English (US) |
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Pages (from-to) | 719-725 |
Number of pages | 7 |
Journal | Nano Letters |
Volume | 10 |
Issue number | 2 |
DOIs | |
State | Published - Feb 10 2010 |
Keywords
- Multiplex
- Nanoarray
- Parylene
- Patterning
- Protein
ASJC Scopus subject areas
- Condensed Matter Physics
- Bioengineering
- General Chemistry
- General Materials Science
- Mechanical Engineering