Nanochannels fabricated in polydimethylsiloxane using sacrificial electrospun polyethylene oxide nanofibers

Leon M. Bellan, Elizabeth A. Strychalski, Harold G. Craighead

Research output: Contribution to journalArticle

27 Scopus citations

Abstract

The authors have used electrospun polyethylene oxide nanofibers as sacrificial templates to form nanofluidic channels in polydimethylsiloxane (PDMS). By depositing fibers on silicon templates incorporating larger structures, the authors demonstrate that these nanochannels can be integrated easily with microfluidics. They use fluorescence microscopy to image channels filled with dye solution. The utility of the hybrid micro- and nanofluidic PDMS structures for single molecule observation and manipulation was demonstrated by introducing single molecules of λ-DNA into the channels. This nanofabrication technique allows the simple construction of integrated micro- and nanofluidic PDMS structures without lithographic nanofabrication techniques.

Original languageEnglish (US)
Pages (from-to)1728-1731
Number of pages4
JournalJournal of Vacuum Science and Technology B: Microelectronics and Nanometer Structures
Volume26
Issue number5
DOIs
StatePublished - 2008

ASJC Scopus subject areas

  • Condensed Matter Physics
  • Electrical and Electronic Engineering

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