Nanochannel systems for personalized therapy and laboratory diagnostics

Alessandro Grattoni, D. Fine, Arturas Ziemys, J. Gill, E. Zabre, R. Goodall, Mauro Ferrari

Research output: Contribution to journalArticlepeer-review

28 Scopus citations

Abstract

Significant recent progress has been made in the development of microfabricated nanofluidic devices for use in the biomedical sciences. Novel nanotechnological approaches have been explored in view of a more individualized medical approach. Much of the development has been fuelled by the advantages derived from utilizing nanoscale phenomena to manipulate fluid samples or mediate drug delivery. As such, we present a comprehensive review of nanochannel technologies, highlighting their potential for diagnostic and therapeutic applications.

Original languageEnglish (US)
Pages (from-to)343-365
Number of pages23
JournalCurrent Pharmaceutical Biotechnology
Volume11
Issue number4
DOIs
StatePublished - 2010

Keywords

  • Drug delivery
  • Mems
  • Microfabrication
  • Nanofluidics
  • Silicon nanotechnology

ASJC Scopus subject areas

  • Pharmaceutical Science
  • Biotechnology

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