Myxedema Coma Associated with Macroprolactinoma: Case Report and Review of the Literature

Elizabeth Jasola Omoniyi, Richard J. Robbins

Research output: Contribution to journalArticlepeer-review

Abstract

Myxedema coma is a rare life-threatening presentation of severe hypothyroidism associated with a high mortality rate. Although most cases are due to primary thyroid failure, a minority have central hypothyroidism as the underlying cause. We report the case of a 69-year-old man who presented with obtundation, hypoglycemia, and hyponatremia. The patient's initial thyroid-stimulating hormone (TSH) was within normal limits. Subsequent evaluation revealed critical anterior pituitary insufficiency due to a macroprolactinoma and a diagnosis of myxedema coma after appropriate workup The finding of a normal serum TSH should not eliminate the possibility of myxedema coma.

Original languageEnglish (US)
Article number1591616
JournalCase Reports in Endocrinology
Volume2022
DOIs
StatePublished - 2022

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism

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