TY - JOUR
T1 - Myxedema Coma Associated with Macroprolactinoma
T2 - Case Report and Review of the Literature
AU - Omoniyi, Elizabeth Jasola
AU - Robbins, Richard J.
N1 - Copyright © 2022 Elizabeth Jasola Omoniyi and Richard J. Robbins.
PY - 2022
Y1 - 2022
N2 - Myxedema coma is a rare life-threatening presentation of severe hypothyroidism associated with a high mortality rate. Although most cases are due to primary thyroid failure, a minority have central hypothyroidism as the underlying cause. We report the case of a 69-year-old man who presented with obtundation, hypoglycemia, and hyponatremia. The patient's initial thyroid-stimulating hormone (TSH) was within normal limits. Subsequent evaluation revealed critical anterior pituitary insufficiency due to a macroprolactinoma and a diagnosis of myxedema coma after appropriate workup The finding of a normal serum TSH should not eliminate the possibility of myxedema coma.
AB - Myxedema coma is a rare life-threatening presentation of severe hypothyroidism associated with a high mortality rate. Although most cases are due to primary thyroid failure, a minority have central hypothyroidism as the underlying cause. We report the case of a 69-year-old man who presented with obtundation, hypoglycemia, and hyponatremia. The patient's initial thyroid-stimulating hormone (TSH) was within normal limits. Subsequent evaluation revealed critical anterior pituitary insufficiency due to a macroprolactinoma and a diagnosis of myxedema coma after appropriate workup The finding of a normal serum TSH should not eliminate the possibility of myxedema coma.
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U2 - 10.1155/2022/1591616
DO - 10.1155/2022/1591616
M3 - Article
C2 - 35528636
AN - SCOPUS:85130063557
SN - 2090-6501
VL - 2022
SP - 1591616
JO - Case Reports in Endocrinology
JF - Case Reports in Endocrinology
M1 - 1591616
ER -