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Myofibroblastoma of the tongue. An immunohistochemical, ultrastructural, and flow cytometric study

A. A. Sahin, Jae Ro, N. G. Ordonez, M. A. Luna, A. K. El-Naggar, H. Goepfert, Alberto Ayala

Research output: Contribution to journalArticlepeer-review

Abstract

A case of myofibroblastoma arising in the tongue of a 77-year-old man is described. The patient presented with a submucosal tongue mass without other associated symptoms. The tumor was 2 cm in diameter, well circumscribed, and composed of uniform spindle cells arranged in fascicles. Electron microscopic examination and immunohistochemistry demonstrated a myofibroblastic origin for the tumor cells. DNA flow cytometric analysis showed a diploid DNA content of this tumor. To the authors' knowledge, this is the first report of myofibroblastoma occurring in the tongue.

Original languageEnglish (US)
Pages (from-to)773-777
Number of pages5
JournalAmerican Journal of Clinical Pathology
Volume94
Issue number6
DOIs
StatePublished - 1990

Keywords

  • Flow cytometry
  • Immunohistochemistry
  • Myofibroblast
  • Myofibroblastoma
  • Tongue

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

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