Myocardial suppression in vivo by spin locking with composite pulses

W. Thomas Dixon, John N. Oshinski, Jon D. Trudeau, Bradley C. Arnold, Roderic I. Pettigrew

Research output: Contribution to journalArticlepeer-review

78 Scopus citations


Improved myocardium-blood contrast by myocardial suppression resulting from T1ρ-weighting in contrast-enhanced, gradient-echo, bright-blood cine images, acquired at 1.5T, is shown. In the standard images, blood has twice the intensity of muscle. In similar T1ρ-weighted images, it has 3-4 times the intensity of muscle. A composite spin-lock pulse before each observation pulse provides T1ρ-weighting. A typical pulse was: 90y-135x-360x-135x-90(- y) with element durations: 0.84, 1.26, 8.12, 1.26, and 0.84 ms. The tolerance of this composite pulse to shimming and frequency errors allows spin locking with comparatively weak RF and therefore low specific absorption rate (SAR). Initial clinical evaluation on patients with poor ventricular function demonstrates both a qualitative and quantitative improvement in delineation of myocardial borders.

Original languageEnglish (US)
Pages (from-to)90-94
Number of pages5
JournalMagnetic Resonance in Medicine
Issue number1
StatePublished - Jul 1996


  • cardiac imaging
  • magnetization-prepared contrast

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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