Myocardial Infarction as a Clinical End Point in Research: What Are We Really Talking About?

Andrew P. Defilippis; Khurram Nasir; Michael J. Blaha

doi:10.1161/CIRCRESAHA.119.315101

Myocardial Infarction as a Clinical End Point in Research: What Are We Really Talking About?

Andrew P. Defilippis, Khurram Nasir, Michael J. Blaha

Research output: Contribution to journal › Review article

4 Scopus citations

Abstract

Reflecting the greater understanding of the many diverse causes of myocardial injury, international consensus definition of myocardial injury now includes nonischemic causes of myocardial injury and several etiologically distinct subtypes of myocardial infarction (MI). It is time that all ongoing prospective cohorts and clinical trials systematically differentiate and report on all the etiologically distinct types of myocardial injury. Such reporting will undoubtedly advance the fundamental understanding of the epidemiology of myocardial injury events, including differing risk factor associations, allowing better prediction, prevention, and pharmacotherapies for all identified subtypes of myocardial injury events-including all subtypes of MI.

Original language	English (US)
Pages (from-to)	1701-1703
Number of pages	3
Journal	Circulation Research
Volume	124
Issue number	12
DOIs	https://doi.org/10.1161/CIRCRESAHA.119.315101
State	Published - Jun 7 2019

Keywords

acute coronary syndrome
ischemia
myocardial infarction
prospective studies
risk factors

ASJC Scopus subject areas

Physiology
Cardiology and Cardiovascular Medicine

Access to Document

10.1161/CIRCRESAHA.119.315101

Fingerprint Dive into the research topics of 'Myocardial Infarction as a Clinical End Point in Research: What Are We Really Talking About?'. Together they form a unique fingerprint.

Cite this

@article{6285966853e64d05be39d307ecabd450,

title = "Myocardial Infarction as a Clinical End Point in Research: What Are We Really Talking About?",

abstract = "Reflecting the greater understanding of the many diverse causes of myocardial injury, international consensus definition of myocardial injury now includes nonischemic causes of myocardial injury and several etiologically distinct subtypes of myocardial infarction (MI). It is time that all ongoing prospective cohorts and clinical trials systematically differentiate and report on all the etiologically distinct types of myocardial injury. Such reporting will undoubtedly advance the fundamental understanding of the epidemiology of myocardial injury events, including differing risk factor associations, allowing better prediction, prevention, and pharmacotherapies for all identified subtypes of myocardial injury events-including all subtypes of MI.",

keywords = "acute coronary syndrome, ischemia, myocardial infarction, prospective studies, risk factors",

author = "Defilippis, {Andrew P.} and Khurram Nasir and Blaha, {Michael J.}",

year = "2019",

month = jun,

day = "7",

doi = "10.1161/CIRCRESAHA.119.315101",

language = "English (US)",

volume = "124",

pages = "1701--1703",

journal = "Circulation Research",

issn = "0009-7330",

publisher = "Lippincott Williams and Wilkins",

number = "12",

}

TY - JOUR

T1 - Myocardial Infarction as a Clinical End Point in Research

T2 - What Are We Really Talking About?

AU - Defilippis, Andrew P.

AU - Nasir, Khurram

AU - Blaha, Michael J.

PY - 2019/6/7

Y1 - 2019/6/7

N2 - Reflecting the greater understanding of the many diverse causes of myocardial injury, international consensus definition of myocardial injury now includes nonischemic causes of myocardial injury and several etiologically distinct subtypes of myocardial infarction (MI). It is time that all ongoing prospective cohorts and clinical trials systematically differentiate and report on all the etiologically distinct types of myocardial injury. Such reporting will undoubtedly advance the fundamental understanding of the epidemiology of myocardial injury events, including differing risk factor associations, allowing better prediction, prevention, and pharmacotherapies for all identified subtypes of myocardial injury events-including all subtypes of MI.

AB - Reflecting the greater understanding of the many diverse causes of myocardial injury, international consensus definition of myocardial injury now includes nonischemic causes of myocardial injury and several etiologically distinct subtypes of myocardial infarction (MI). It is time that all ongoing prospective cohorts and clinical trials systematically differentiate and report on all the etiologically distinct types of myocardial injury. Such reporting will undoubtedly advance the fundamental understanding of the epidemiology of myocardial injury events, including differing risk factor associations, allowing better prediction, prevention, and pharmacotherapies for all identified subtypes of myocardial injury events-including all subtypes of MI.

KW - acute coronary syndrome

KW - ischemia

KW - myocardial infarction

KW - prospective studies

KW - risk factors

UR - http://www.scopus.com/inward/record.url?scp=85067500641&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85067500641&partnerID=8YFLogxK

U2 - 10.1161/CIRCRESAHA.119.315101

DO - 10.1161/CIRCRESAHA.119.315101

M3 - Review article

C2 - 31170039

AN - SCOPUS:85067500641

VL - 124

SP - 1701

EP - 1703

JO - Circulation Research

JF - Circulation Research

SN - 0009-7330

IS - 12

ER -