Myocardial bridging: Contemporary understanding of pathophysiology with implications for diagnostic and therapeutic strategies

Michel T. Corban; Olivia Y. Hung; Parham Eshtehardi; Emad Rasoul-Arzrumly; Michael McDaniel; Girum Mekonnen; Lucas H. Timmins; Jerre Lutz; Robert A. Guyton; Habib Samady

doi:10.1016/j.jacc.2014.01.049

Myocardial bridging: Contemporary understanding of pathophysiology with implications for diagnostic and therapeutic strategies

Michel T. Corban, Olivia Y. Hung, Parham Eshtehardi, Emad Rasoul-Arzrumly, Michael McDaniel, Girum Mekonnen, Lucas H. Timmins, Jerre Lutz, Robert A. Guyton, Habib Samady

Research output: Contribution to journal › Review article › peer-review

216 Scopus citations

Abstract

Patients with myocardial bridging are often asymptomatic, but this anomaly may be associated with exertional angina, acute coronary syndromes, cardiac arrhythmias, syncope, or even sudden cardiac death. This review presents our understanding of the pathophysiology of myocardial bridging and describes prevailing diagnostic modalities and therapeutic options for this challenging clinical entity.

Original language	English (US)
Pages (from-to)	2346-2355
Number of pages	10
Journal	Journal of the American College of Cardiology
Volume	63
Issue number	22
DOIs	https://doi.org/10.1016/j.jacc.2014.01.049
State	Published - Jun 10 2014

Keywords

coronary wall shear stress
intracoronary Doppler velocity and pressure
intravascular imaging
myocardial bridge
myotomy
percutaneous coronary intervention

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

Access to Document

10.1016/j.jacc.2014.01.049

Cite this

Corban, M. T., Hung, O. Y., Eshtehardi, P., Rasoul-Arzrumly, E., McDaniel, M., Mekonnen, G., Timmins, L. H., Lutz, J., Guyton, R. A., & Samady, H. (2014). Myocardial bridging: Contemporary understanding of pathophysiology with implications for diagnostic and therapeutic strategies. Journal of the American College of Cardiology, 63(22), 2346-2355. https://doi.org/10.1016/j.jacc.2014.01.049

Corban, MT, Hung, OY, Eshtehardi, P, Rasoul-Arzrumly, E, McDaniel, M, Mekonnen, G, Timmins, LH, Lutz, J, Guyton, RA & Samady, H 2014, 'Myocardial bridging: Contemporary understanding of pathophysiology with implications for diagnostic and therapeutic strategies', Journal of the American College of Cardiology, vol. 63, no. 22, pp. 2346-2355. https://doi.org/10.1016/j.jacc.2014.01.049

@article{cf54b1b4e0064bca8305884c3b2e24db,

title = "Myocardial bridging: Contemporary understanding of pathophysiology with implications for diagnostic and therapeutic strategies",

abstract = "Patients with myocardial bridging are often asymptomatic, but this anomaly may be associated with exertional angina, acute coronary syndromes, cardiac arrhythmias, syncope, or even sudden cardiac death. This review presents our understanding of the pathophysiology of myocardial bridging and describes prevailing diagnostic modalities and therapeutic options for this challenging clinical entity.",

keywords = "coronary wall shear stress, intracoronary Doppler velocity and pressure, intravascular imaging, myocardial bridge, myotomy, percutaneous coronary intervention",

author = "Corban, {Michel T.} and Hung, {Olivia Y.} and Parham Eshtehardi and Emad Rasoul-Arzrumly and Michael McDaniel and Girum Mekonnen and Timmins, {Lucas H.} and Jerre Lutz and Guyton, {Robert A.} and Habib Samady",

note = "Funding Information: Dr. Hung is supported by the Ruth L. Kirschstein National Research Service Awards training grant ( 5T32HL007745 ). Dr. Mekonnen is supported by a grant from the National Heart, Lung, and Blood Institute of the National Institutes of Health ( P01HL101398 ). Dr. Timmins is supported by an American Heart Association Postdoctoral Fellowship ( 11POST7210012 ). Dr. Guyton is a consultant for Medtronic, Inc. Dr. Samady receives research funding from Volcano Corp., St. Jude Medical, Toshiba, and Forest Pharmaceuticals. All other authors have reported that they have no relationships relevant to the contents of this paper to disclose. Drs. Corban and Hung contributed equally to this work. ",

year = "2014",

month = jun,

day = "10",

doi = "10.1016/j.jacc.2014.01.049",

language = "English (US)",

volume = "63",

pages = "2346--2355",

journal = "Journal of the American College of Cardiology",

issn = "0735-1097",

publisher = "Elsevier",

number = "22",

}

TY - JOUR

T1 - Myocardial bridging

T2 - Contemporary understanding of pathophysiology with implications for diagnostic and therapeutic strategies

AU - Corban, Michel T.

AU - Hung, Olivia Y.

AU - Eshtehardi, Parham

AU - Rasoul-Arzrumly, Emad

AU - McDaniel, Michael

AU - Mekonnen, Girum

AU - Timmins, Lucas H.

AU - Lutz, Jerre

AU - Guyton, Robert A.

AU - Samady, Habib

N1 - Funding Information: Dr. Hung is supported by the Ruth L. Kirschstein National Research Service Awards training grant ( 5T32HL007745 ). Dr. Mekonnen is supported by a grant from the National Heart, Lung, and Blood Institute of the National Institutes of Health ( P01HL101398 ). Dr. Timmins is supported by an American Heart Association Postdoctoral Fellowship ( 11POST7210012 ). Dr. Guyton is a consultant for Medtronic, Inc. Dr. Samady receives research funding from Volcano Corp., St. Jude Medical, Toshiba, and Forest Pharmaceuticals. All other authors have reported that they have no relationships relevant to the contents of this paper to disclose. Drs. Corban and Hung contributed equally to this work.

PY - 2014/6/10

Y1 - 2014/6/10

N2 - Patients with myocardial bridging are often asymptomatic, but this anomaly may be associated with exertional angina, acute coronary syndromes, cardiac arrhythmias, syncope, or even sudden cardiac death. This review presents our understanding of the pathophysiology of myocardial bridging and describes prevailing diagnostic modalities and therapeutic options for this challenging clinical entity.

AB - Patients with myocardial bridging are often asymptomatic, but this anomaly may be associated with exertional angina, acute coronary syndromes, cardiac arrhythmias, syncope, or even sudden cardiac death. This review presents our understanding of the pathophysiology of myocardial bridging and describes prevailing diagnostic modalities and therapeutic options for this challenging clinical entity.

KW - coronary wall shear stress

KW - intracoronary Doppler velocity and pressure

KW - intravascular imaging

KW - myocardial bridge

KW - myotomy

KW - percutaneous coronary intervention

UR - http://www.scopus.com/inward/record.url?scp=84902094672&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84902094672&partnerID=8YFLogxK

U2 - 10.1016/j.jacc.2014.01.049

DO - 10.1016/j.jacc.2014.01.049

M3 - Review article

C2 - 24583304

AN - SCOPUS:84902094672

SN - 0735-1097

VL - 63

SP - 2346

EP - 2355

JO - Journal of the American College of Cardiology

JF - Journal of the American College of Cardiology

IS - 22

ER -

Myocardial bridging: Contemporary understanding of pathophysiology with implications for diagnostic and therapeutic strategies

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this