Myeloid Notch1 deficiency activates the RhoA/ROCK pathway and aggravates hepatocellular damage in mouse ischemic livers

Medicine and Dentistry

• Ischemia 100%
• Amino Terminal Sequence 100%
• Phosphatase 100%
• Liver Cell Damage 100%
• Tensin 100%
• Liver Ischemia 100%
• Transcription Factor HES 1 100%
• Phosphotransferase 75%
• Ras Signaling 75%
• Multigene Family 75%
• Toll Like Receptor 4 75%
• Macrophage 50%
• In Vitro 50%
• Notch Signaling 50%
• Reperfusion Injury 50%
• Innate Immunity 25%
• Neutrophil 25%
• Leukocyte 25%
• Cell Function 25%
• Immune Response 25%
• Genetic Transfection 25%
• Programmed Cell Death 25%
• Mediator 25%
• Cell Signaling Pathway 25%
• Tissue Injury 25%
• Serositis 25%
• Alanine Aminotransferase 25%
• Repressor Gene 25%
• Immunocompetent Cell 25%
• Lipopolysaccharide 25%
• Cell Maturation 25%
• Synapsin I 25%
• Intracellular Signaling 25%
• Notch Receptor 25%
• Lentivirus 25%
• Hepatology 25%
• Inflammatory Injury 25%
• Stress Activated Protein Kinase 25%
• Rho-Associated Protein Kinase 25%
• Scaffold Protein 25%
• CRISPR Associated Protein 25%
• Protein Kinase B 25%

Keyphrases

• Liver 100%
• Notch1 100%
• RhoA-ROCK Pathway 100%
• Hepatocellular Damage 100%
• C-Jun N-terminal Kinase 66%
• Phosphatase 66%
• Tensin Homolog 66%
• Hairy and Enhancer of Split 1 66%
• Ischemia 50%
• Toll-like 50%
• Reperfusion 50%
• Ras Homolog Gene Family Member A 50%
• Macrophages 33%
• Ischemia-reperfusion Injury 33%
• Notch Signaling 33%
• Liver Inflammation 33%
• Ischemia Injury 33%
• ROCK Pathway 33%
• Inflammation 16%
• Innate Immunity 16%
• Mouse Model 16%
• Transcriptional Repressor 16%
• Immune Response 16%
• Inflammatory Mediators 16%
• Kinase Activation 16%
• Therapeutic Potential 16%
• Transplant Recipients 16%
• Inflammatory Response 16%
• In Vitro Study 16%
• Knockdown 16%
• Novel Regulator 16%
• Ablation 16%
• Immune Cell Function 16%
• Lipopolysaccharide 16%
• Notch Receptors 16%
• Intracellular Signaling 16%
• Tissue Injury 16%
• Notch Intracellular Domain 16%
• Serum Alanine Aminotransferase 16%
• Alanine Aminotransferase Level 16%
• Lentivirus 16%
• Organ Ischemia 16%
• Hepatocellular Injury 16%
• Leukocyte Accumulation 16%
• Scaffold Protein 16%
• Rho Kinase 16%
• Hepatology 16%
• Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) 16%
• Hepatocyte Apoptosis 16%
• Hepatocellular Function 16%
• Neutrophil Trafficking 16%
• Liver Ischemia 16%
• Immune Cell Development 16%
• Anti-CRISPR Proteins 16%

Immunology and Microbiology

• Myeloid 100%
• Reperfusion 100%
• Amino Terminal Sequence 80%
• Transcription Factor HES 1 80%
• Phosphatase 80%
• TLR4 60%
• Multigene Family 60%
• Macrophage 40%
• Notch Signaling 40%
• In Vitro 40%
• Cell Function 20%
• Mouse Model 20%
• Innate Immune System 20%
• Immune Response 20%
• Leukocyte 20%
• Neutrophil 20%
• Mediator 20%
• Repressor Gene 20%
• Immunocompetent Cell 20%
• Programmed Cell Death 20%
• Inflammation Response 20%
• Genetic Transfection 20%
• Notch 20%
• Cell Maturation 20%
• Intracellular Signaling 20%
• Inflammatory Injury 20%
• Alanine Aminotransferase Blood Level 20%
• Alanine Aminotransferase Level 20%
• Lentivirus 20%
• Clustered Regularly Interspaced Short Palindromic Repeat 20%
• Hepatology 20%