Myelodysplasia with isolated trisomy 15: A 15-Year follow-up without specific therapy

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5 Scopus citations


A 41-year-old patient manifested pancytopenia with macrocytosis following pesticide exposure. She was later found to have myelodysplasia with trisomy 15. Over a 15-year period of observation, and with no specific therapy, her hematological disorder remains stable, despite persistence of the chromosomal aberration. This and similar reported observations suggest that the course of this uncommon form of myelodysplasia is often indolent and not accurately predicted by application of the widely used International Prognostic Scoring System for the myelodysplastic syndromes.

Original languageEnglish (US)
Pages (from-to)157-158
Number of pages2
JournalAmerican Journal of the Medical Sciences
Issue number3
StatePublished - Mar 1 2006


  • IPSS
  • Macrocytosis
  • Myelodysplasia
  • Pancytopenia
  • Trisomy 15

ASJC Scopus subject areas

  • Medicine(all)


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