Mycobacterium abscessus in cystic fibrosis lung transplant recipients: Report of 2 cases and risk for recurrence

S. Zaidi; O. Elidemir; J. S. Heinle; E. D. McKenzie; M. G. Schecter; S. L. Kaplan; M. K. Dishop; D. L. Kearney; G. B. Mallory

doi:10.1111/j.1399-3062.2009.00378.x

Mycobacterium abscessus in cystic fibrosis lung transplant recipients: Report of 2 cases and risk for recurrence

S. Zaidi, O. Elidemir, J. S. Heinle, E. D. McKenzie, M. G. Schecter, S. L. Kaplan, M. K. Dishop, D. L. Kearney, G. B. Mallory

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50 Scopus citations

Abstract

Mycobacterium abscessus is increasingly recognized as an important pathogen in some individuals with advancing lung disease related to cystic fibrosis (CF). Because of its resistance to antimicrobial agents and virulence, its presence in the lungs of potential lung transplant recipients can be problematic. We present 2 cases of individuals with CF in whom M. abscessus was present in the preoperative sputum cultures. The organism manifested different degrees of invasiveness in the 2 cases after transplantation with different outcomes, suggesting an approach to future candidates for lung transplantation that may be of clinical significance to their physicians and surgeons.

Original language	English (US)
Pages (from-to)	243-248
Number of pages	6
Journal	Transplant Infectious Disease
Volume	11
Issue number	3
DOIs	https://doi.org/10.1111/j.1399-3062.2009.00378.x
State	Published - Jun 2009

Keywords

Cystic fibrosis
Lung transplantation
Mycobacterium abscessus
Non-tuberculous mycobacteria

ASJC Scopus subject areas

Transplantation
Infectious Diseases

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10.1111/j.1399-3062.2009.00378.x

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title = "Mycobacterium abscessus in cystic fibrosis lung transplant recipients: Report of 2 cases and risk for recurrence",

abstract = "Mycobacterium abscessus is increasingly recognized as an important pathogen in some individuals with advancing lung disease related to cystic fibrosis (CF). Because of its resistance to antimicrobial agents and virulence, its presence in the lungs of potential lung transplant recipients can be problematic. We present 2 cases of individuals with CF in whom M. abscessus was present in the preoperative sputum cultures. The organism manifested different degrees of invasiveness in the 2 cases after transplantation with different outcomes, suggesting an approach to future candidates for lung transplantation that may be of clinical significance to their physicians and surgeons.",

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AU - Zaidi, S.

AU - Elidemir, O.

AU - Heinle, J. S.

AU - McKenzie, E. D.

AU - Schecter, M. G.

AU - Kaplan, S. L.

AU - Dishop, M. K.

AU - Kearney, D. L.

AU - Mallory, G. B.

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AB - Mycobacterium abscessus is increasingly recognized as an important pathogen in some individuals with advancing lung disease related to cystic fibrosis (CF). Because of its resistance to antimicrobial agents and virulence, its presence in the lungs of potential lung transplant recipients can be problematic. We present 2 cases of individuals with CF in whom M. abscessus was present in the preoperative sputum cultures. The organism manifested different degrees of invasiveness in the 2 cases after transplantation with different outcomes, suggesting an approach to future candidates for lung transplantation that may be of clinical significance to their physicians and surgeons.

KW - Cystic fibrosis

KW - Lung transplantation

KW - Mycobacterium abscessus

KW - Non-tuberculous mycobacteria

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Mycobacterium abscessus in cystic fibrosis lung transplant recipients: Report of 2 cases and risk for recurrence

Abstract

Keywords

ASJC Scopus subject areas

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