Mycobacterium abscessus in cystic fibrosis lung transplant recipients: Report of 2 cases and risk for recurrence

S. Zaidi, O. Elidemir, J. S. Heinle, E. D. McKenzie, M. G. Schecter, Sheldon Kaplan, M. K. Dishop, D. L. Kearney, G. B. Mallory

Research output: Contribution to journalArticle

39 Scopus citations

Abstract

Mycobacterium abscessus is increasingly recognized as an important pathogen in some individuals with advancing lung disease related to cystic fibrosis (CF). Because of its resistance to antimicrobial agents and virulence, its presence in the lungs of potential lung transplant recipients can be problematic. We present 2 cases of individuals with CF in whom M. abscessus was present in the preoperative sputum cultures. The organism manifested different degrees of invasiveness in the 2 cases after transplantation with different outcomes, suggesting an approach to future candidates for lung transplantation that may be of clinical significance to their physicians and surgeons.

Original languageEnglish (US)
Pages (from-to)243-248
Number of pages6
JournalTransplant Infectious Disease
Volume11
Issue number3
DOIs
StatePublished - Jun 1 2009

Keywords

  • Cystic fibrosis
  • Lung transplantation
  • Mycobacterium abscessus
  • Non-tuberculous mycobacteria

ASJC Scopus subject areas

  • Transplantation
  • Infectious Diseases

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