Mycobacterium abscessus in cystic fibrosis lung transplant recipients: Report of 2 cases and risk for recurrence

S. Zaidi, O. Elidemir, J. S. Heinle, E. D. McKenzie, M. G. Schecter, S. L. Kaplan, M. K. Dishop, D. L. Kearney, G. B. Mallory

    Research output: Contribution to journalArticlepeer-review

    50 Scopus citations

    Abstract

    Mycobacterium abscessus is increasingly recognized as an important pathogen in some individuals with advancing lung disease related to cystic fibrosis (CF). Because of its resistance to antimicrobial agents and virulence, its presence in the lungs of potential lung transplant recipients can be problematic. We present 2 cases of individuals with CF in whom M. abscessus was present in the preoperative sputum cultures. The organism manifested different degrees of invasiveness in the 2 cases after transplantation with different outcomes, suggesting an approach to future candidates for lung transplantation that may be of clinical significance to their physicians and surgeons.

    Original languageEnglish (US)
    Pages (from-to)243-248
    Number of pages6
    JournalTransplant Infectious Disease
    Volume11
    Issue number3
    DOIs
    StatePublished - Jun 2009

    Keywords

    • Cystic fibrosis
    • Lung transplantation
    • Mycobacterium abscessus
    • Non-tuberculous mycobacteria

    ASJC Scopus subject areas

    • Transplantation
    • Infectious Diseases

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