Mycobacterium abscessus in cystic fibrosis lung transplant recipients: Report of 2 cases and risk for recurrence

S. Zaidi; O. Elidemir; J. S. Heinle; E. D. McKenzie; M. G. Schecter; S. L. Kaplan; M. K. Dishop; D. L. Kearney; G. B. Mallory

doi:10.1111/j.1399-3062.2009.00378.x

Mycobacterium abscessus in cystic fibrosis lung transplant recipients: Report of 2 cases and risk for recurrence

S. Zaidi, O. Elidemir, J. S. Heinle, E. D. McKenzie, M. G. Schecter, S. L. Kaplan, M. K. Dishop, D. L. Kearney, G. B. Mallory

Research Institute

Research output: Contribution to journal › Article › peer-review

44 Scopus citations

Abstract

Mycobacterium abscessus is increasingly recognized as an important pathogen in some individuals with advancing lung disease related to cystic fibrosis (CF). Because of its resistance to antimicrobial agents and virulence, its presence in the lungs of potential lung transplant recipients can be problematic. We present 2 cases of individuals with CF in whom M. abscessus was present in the preoperative sputum cultures. The organism manifested different degrees of invasiveness in the 2 cases after transplantation with different outcomes, suggesting an approach to future candidates for lung transplantation that may be of clinical significance to their physicians and surgeons.

Original language	English (US)
Pages (from-to)	243-248
Number of pages	6
Journal	Transplant Infectious Disease
Volume	11
Issue number	3
DOIs	https://doi.org/10.1111/j.1399-3062.2009.00378.x
State	Published - Jun 2009

Keywords

Cystic fibrosis
Lung transplantation
Mycobacterium abscessus
Non-tuberculous mycobacteria

ASJC Scopus subject areas

Transplantation
Infectious Diseases

Access to Document

10.1111/j.1399-3062.2009.00378.x

Cite this

@article{d516c0a2e085495fb025e5fe3e40e6a6,

title = "Mycobacterium abscessus in cystic fibrosis lung transplant recipients: Report of 2 cases and risk for recurrence",

abstract = "Mycobacterium abscessus is increasingly recognized as an important pathogen in some individuals with advancing lung disease related to cystic fibrosis (CF). Because of its resistance to antimicrobial agents and virulence, its presence in the lungs of potential lung transplant recipients can be problematic. We present 2 cases of individuals with CF in whom M. abscessus was present in the preoperative sputum cultures. The organism manifested different degrees of invasiveness in the 2 cases after transplantation with different outcomes, suggesting an approach to future candidates for lung transplantation that may be of clinical significance to their physicians and surgeons.",

keywords = "Cystic fibrosis, Lung transplantation, Mycobacterium abscessus, Non-tuberculous mycobacteria",

author = "S. Zaidi and O. Elidemir and Heinle, {J. S.} and McKenzie, {E. D.} and Schecter, {M. G.} and Kaplan, {S. L.} and Dishop, {M. K.} and Kearney, {D. L.} and Mallory, {G. B.}",

year = "2009",

month = jun,

doi = "10.1111/j.1399-3062.2009.00378.x",

language = "English (US)",

volume = "11",

pages = "243--248",

journal = "Transplant Infectious Disease",

issn = "1398-2273",

publisher = "Wiley",

number = "3",

}

TY - JOUR

T1 - Mycobacterium abscessus in cystic fibrosis lung transplant recipients

T2 - Report of 2 cases and risk for recurrence

AU - Zaidi, S.

AU - Elidemir, O.

AU - Heinle, J. S.

AU - McKenzie, E. D.

AU - Schecter, M. G.

AU - Kaplan, S. L.

AU - Dishop, M. K.

AU - Kearney, D. L.

AU - Mallory, G. B.

PY - 2009/6

Y1 - 2009/6

N2 - Mycobacterium abscessus is increasingly recognized as an important pathogen in some individuals with advancing lung disease related to cystic fibrosis (CF). Because of its resistance to antimicrobial agents and virulence, its presence in the lungs of potential lung transplant recipients can be problematic. We present 2 cases of individuals with CF in whom M. abscessus was present in the preoperative sputum cultures. The organism manifested different degrees of invasiveness in the 2 cases after transplantation with different outcomes, suggesting an approach to future candidates for lung transplantation that may be of clinical significance to their physicians and surgeons.

AB - Mycobacterium abscessus is increasingly recognized as an important pathogen in some individuals with advancing lung disease related to cystic fibrosis (CF). Because of its resistance to antimicrobial agents and virulence, its presence in the lungs of potential lung transplant recipients can be problematic. We present 2 cases of individuals with CF in whom M. abscessus was present in the preoperative sputum cultures. The organism manifested different degrees of invasiveness in the 2 cases after transplantation with different outcomes, suggesting an approach to future candidates for lung transplantation that may be of clinical significance to their physicians and surgeons.

KW - Cystic fibrosis

KW - Lung transplantation

KW - Mycobacterium abscessus

KW - Non-tuberculous mycobacteria

UR - http://www.scopus.com/inward/record.url?scp=67149120801&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=67149120801&partnerID=8YFLogxK

U2 - 10.1111/j.1399-3062.2009.00378.x

DO - 10.1111/j.1399-3062.2009.00378.x

M3 - Article

C2 - 19298240

AN - SCOPUS:67149120801

VL - 11

SP - 243

EP - 248

JO - Transplant Infectious Disease

JF - Transplant Infectious Disease

SN - 1398-2273

IS - 3

ER -

Mycobacterium abscessus in cystic fibrosis lung transplant recipients: Report of 2 cases and risk for recurrence

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this