Mutant KRAS Exosomes Alter the Metabolic State of Recipient Colonic Epithelial Cells

Qin Zhang; Dennis K. Jeppesen; James N. Higginbotham; Michelle Demory Beckler; Emily J. Poulin; Alex J. Walsh; Melissa C. Skala; Eliot T. McKinley; H. Charles Manning; Matthew R. Hight; Michael L. Schulte; Kimberly R. Watt; G. Daniel Ayers; Melissa M. Wolf; Gabriela Andrejeva; Jeffrey C. Rathmell; Jeffrey L. Franklin; Robert J. Coffey

doi:10.1016/j.jcmgh.2018.01.013

Mutant KRAS Exosomes Alter the Metabolic State of Recipient Colonic Epithelial Cells

Qin Zhang, Dennis K. Jeppesen, James N. Higginbotham, Michelle Demory Beckler, Emily J. Poulin, Alex J. Walsh, Melissa C. Skala, Eliot T. McKinley, H. Charles Manning, Matthew R. Hight, Michael L. Schulte, Kimberly R. Watt, G. Daniel Ayers, Melissa M. Wolf, Gabriela Andrejeva, Jeffrey C. Rathmell, Jeffrey L. Franklin, Robert J. Coffey

Research output: Contribution to journal › Article › peer-review

28 Scopus citations

Original language	English (US)
Pages (from-to)	627-629.e6
Journal	CMGH
Volume	5
Issue number	4
DOIs	https://doi.org/10.1016/j.jcmgh.2018.01.013
State	Published - 2018

ASJC Scopus subject areas

Hepatology
Gastroenterology

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10.1016/j.jcmgh.2018.01.013

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Zhang, Q., Jeppesen, D. K., Higginbotham, J. N., Demory Beckler, M., Poulin, E. J., Walsh, A. J., Skala, M. C., McKinley, E. T., Manning, H. C., Hight, M. R., Schulte, M. L., Watt, K. R., Ayers, G. D., Wolf, M. M., Andrejeva, G., Rathmell, J. C., Franklin, J. L., & Coffey, R. J. (2018). Mutant KRAS Exosomes Alter the Metabolic State of Recipient Colonic Epithelial Cells. CMGH, 5(4), 627-629.e6. https://doi.org/10.1016/j.jcmgh.2018.01.013

Zhang, Q, Jeppesen, DK, Higginbotham, JN, Demory Beckler, M, Poulin, EJ, Walsh, AJ, Skala, MC, McKinley, ET, Manning, HC, Hight, MR, Schulte, ML, Watt, KR, Ayers, GD, Wolf, MM, Andrejeva, G, Rathmell, JC, Franklin, JL & Coffey, RJ 2018, 'Mutant KRAS Exosomes Alter the Metabolic State of Recipient Colonic Epithelial Cells', CMGH, vol. 5, no. 4, pp. 627-629.e6. https://doi.org/10.1016/j.jcmgh.2018.01.013

@article{39fee30cf4394ad5ba602e7bf8aa87a9,

title = "Mutant KRAS Exosomes Alter the Metabolic State of Recipient Colonic Epithelial Cells",

author = "Qin Zhang and Jeppesen, {Dennis K.} and Higginbotham, {James N.} and {Demory Beckler}, Michelle and Poulin, {Emily J.} and Walsh, {Alex J.} and Skala, {Melissa C.} and McKinley, {Eliot T.} and Manning, {H. Charles} and Hight, {Matthew R.} and Schulte, {Michael L.} and Watt, {Kimberly R.} and Ayers, {G. Daniel} and Wolf, {Melissa M.} and Gabriela Andrejeva and Rathmell, {Jeffrey C.} and Franklin, {Jeffrey L.} and Coffey, {Robert J.}",

note = "Funding Information: Funding Supported by National Cancer Institute grants R01 CA163563, U19 CA179514, R35 CA197570, and GI Special Programs of Research Excellence P50 CA 095103 (R.J.C.), NCI HCM R25 CA092043 (M.D.B.), and NIDDK DDRC pilot grant P30 DK058404 (J.L.F.). The Vanderbilt University Flow Cytometry Shared Resource and Center for Small Animal Imaging and the Radiochemistry Core Service are supported by the Vanderbilt Ingram Cancer Center (P30 CA68485) and the Vanderbilt Digestive Disease Research Center (P30 DK058404). The Radiochemistry Core Service also is supported by National Institutes of Health Shared Instrumentation grants S10 OD023543 and OD019963 (H.C.M.).",

year = "2018",

doi = "10.1016/j.jcmgh.2018.01.013",

language = "English (US)",

volume = "5",

pages = "627--629.e6",

journal = "CMGH Cellular and Molecular Gastroenterology and Hepatology",

issn = "2352-345X",

publisher = "Elsevier",

number = "4",

}

TY - JOUR

T1 - Mutant KRAS Exosomes Alter the Metabolic State of Recipient Colonic Epithelial Cells

AU - Zhang, Qin

AU - Jeppesen, Dennis K.

AU - Higginbotham, James N.

AU - Demory Beckler, Michelle

AU - Poulin, Emily J.

AU - Walsh, Alex J.

AU - Skala, Melissa C.

AU - McKinley, Eliot T.

AU - Manning, H. Charles

AU - Hight, Matthew R.

AU - Schulte, Michael L.

AU - Watt, Kimberly R.

AU - Ayers, G. Daniel

AU - Wolf, Melissa M.

AU - Andrejeva, Gabriela

AU - Rathmell, Jeffrey C.

AU - Franklin, Jeffrey L.

AU - Coffey, Robert J.

N1 - Funding Information: Funding Supported by National Cancer Institute grants R01 CA163563, U19 CA179514, R35 CA197570, and GI Special Programs of Research Excellence P50 CA 095103 (R.J.C.), NCI HCM R25 CA092043 (M.D.B.), and NIDDK DDRC pilot grant P30 DK058404 (J.L.F.). The Vanderbilt University Flow Cytometry Shared Resource and Center for Small Animal Imaging and the Radiochemistry Core Service are supported by the Vanderbilt Ingram Cancer Center (P30 CA68485) and the Vanderbilt Digestive Disease Research Center (P30 DK058404). The Radiochemistry Core Service also is supported by National Institutes of Health Shared Instrumentation grants S10 OD023543 and OD019963 (H.C.M.).

PY - 2018

Y1 - 2018

UR - http://www.scopus.com/inward/record.url?scp=85044615467&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85044615467&partnerID=8YFLogxK

U2 - 10.1016/j.jcmgh.2018.01.013

DO - 10.1016/j.jcmgh.2018.01.013

M3 - Article

AN - SCOPUS:85044615467

VL - 5

SP - 627-629.e6

JO - CMGH Cellular and Molecular Gastroenterology and Hepatology

JF - CMGH Cellular and Molecular Gastroenterology and Hepatology

SN - 2352-345X

IS - 4

ER -

Mutant KRAS Exosomes Alter the Metabolic State of Recipient Colonic Epithelial Cells

ASJC Scopus subject areas

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